Want FREE Templates on Digital Transformation? Download our FREE compilation of 50+ slides. This is an exclusive promotion being run on LinkedIn.






Marcus Insights
African Pharma R&D: Partnering for Tropical Disease Solutions


Need help finding what you need? Say hello to Marcus. Based on our proprietary MARC [?] technology, Marcus will search our vast database of management topics and best practice documents to identify the most relevant to your specific, unique business situation. This tool is still in beta. If you have any suggestions or questions, please let us know at support@flevy.com.

Role: VP of R&D
Industry: Pharmaceuticals in Africa

Situation: Leading the research and development department of a pharmaceutical company in Africa, tasked with developing affordable medications for tropical diseases often neglected by the global healthcare industry. Challenges include securing funding for research, navigating diverse regulatory environments, and establishing clinical trial protocols in regions with infrastructure deficits. Our hypothesis is that by collaborating with local governments and international health organizations, we can accelerate drug development and distribution.

Question to Marcus:


Seeking collaboration frameworks for global health initiatives.


Ask Marcus a Question

Based on your specific organizational details captured above, Marcus recommends the following areas for evaluation (in roughly decreasing priority). If you need any further clarification or details on the specific frameworks and concepts described below, please contact us: support@flevy.com.

Stakeholder Management

Engaging stakeholders effectively is crucial for securing funding and support for R&D in tropical diseases. Establish local partnerships with governmental health agencies and international organizations like the WHO to gain access to resources, knowledge, and networks.

These collaborations could lead to co-funding initiatives, shared research, and expedited regulatory processes. Prioritize building transparent relationships with stakeholders to align objectives and ensure the smooth progression of R&D projects, while also establishing trust within the communities where clinical trials may take place.

Learn more about Stakeholder Management

Regulatory Environment

Understanding and navigating the regulatory environment is vital for the approval and distribution of new medications. Work closely with local authorities to comply with diverse regulatory requirements across different African regions.

Develop a regulatory strategy that anticipates potential hurdles in the approval process. Consider creating a specialized regulatory affairs team within your department to focus on harmonizing clinical trial protocols with international standards, which can facilitate faster drug approval and distribution.

Learn more about Environmental, Social, and Governance

Global Health Initiatives

Explore frameworks for collaboration such as Public-Private Partnerships (PPPs), advance market commitments (AMCs), and product development partnerships (PDPs) to further global health initiatives in the region. By leveraging these frameworks, your company can attract investment, share risks, and align incentives with partners.

Additionally, consider participating in disease-specific consortia that bring together multiple stakeholders to focus on R&D for neglected tropical diseases, ensuring that the medications developed are accessible and affordable.

Learn more about Public-Private Partnership Globalization

Funding & Investments

Identify innovative funding mechanisms dedicated to neglected diseases, such as pooled funds, social impact bonds, or venture philanthropy. Present a strong Business Case to global funders, like the Global Fund to Fight AIDS, Tuberculosis and Malaria, emphasizing the potential impact and market for treatments in neglected areas.

Also, explore opportunities for 'blended finance' where public and philanthropic funds de-risk investments to attract private capital.

Learn more about Business Case

Clinical Trials & Research Protocols

Establish robust clinical trial protocols by incorporating Best Practices from developed regions, adapted to local conditions. Address infrastructure deficits by partnering with local hospitals and research institutions, and invest in mobile health technologies for better data collection and patient monitoring.

Ensure that trial designs are culturally sensitive and ethical, with the potential to strengthen local healthcare systems through capacity building and training.

Learn more about Best Practices

Strategic Plan Example

Develop a comprehensive strategic plan that outlines long-term goals for drug development, manufacturing, and distribution. The plan should include detailed analyses of market needs, potential partnerships, and revenue models.

It should also address how to overcome infrastructure challenges, foster local talent for research and development, and ensure the sustainability of operations. This plan will serve as a roadmap for the company's efforts to tackle neglected tropical diseases and can be used to communicate the vision to stakeholders for buy-in and support.

Learn more about Strategic Plan Example

Partnership Development

Form strategic alliances with universities, NGOs, and biotech firms to accelerate the research and commercialization of new drugs. These partnerships can provide access to novel technologies, specialized expertise, and additional resources.

Develop a partnership framework that allows for shared intellectual property rights and equitable distribution of benefits, ensuring that all parties are incentivized to contribute to the success of the joint initiatives.

Learn more about Partnership Agreement

Innovation Management

Encourage a culture of innovation within your R&D department to foster the development of new treatments. Utilize Open Innovation platforms to crowdsource ideas and solutions from researchers worldwide.

Implement an internal system for continuous innovation, encouraging your team to propose and experiment with new approaches to drug development. Monitor and implement emerging technologies that can streamline R&D processes, such as Artificial Intelligence for drug discovery.

Learn more about Artificial Intelligence Open Innovation Innovation Management

Supply Chain Resilience

Build a resilient Supply Chain for the procurement of raw materials and distribution of medications. Diversify suppliers to mitigate risks and ensure the continuous availability of key components for drug production.

Invest in supply chain technologies for better visibility and control. Consider local production facilities to reduce dependency on imports and enhance the ability to respond quickly to local market demands.

Learn more about Supply Chain Supply Chain Resilience

Risk Management

Implement comprehensive Risk Management strategies to anticipate and mitigate risks associated with R&D and operations in Africa. Carry out regular risk assessments to identify potential financial, regulatory, and operational obstacles.

Develop contingency plans for critical risks, such as political instability, currency fluctuations, or supply chain disruptions. Create a risk-aware culture within the company to ensure that all employees understand their role in managing and reporting risks.

Learn more about Risk Management

Did you know?
The average daily rate of a McKinsey consultant is $6,625 (not including expenses). The average price of a Flevy document is $65.


How did Marcus do? Let us know. This tool is still in beta. We would appreciate any feedback you could provide us: support@flevy.com.

If you have any other questions, you can ask Marcus again here.




Trusted by over 10,000+ Client Organizations
Since 2012, we have provided best practices to over 10,000 businesses and organizations of all sizes, from startups and small businesses to the Fortune 100, in over 130 countries.
AT&T GE Cisco Intel IBM Coke Dell Toyota HP Nike Samsung Microsoft Astrazeneca JP Morgan KPMG Walgreens Walmart 3M Kaiser Oracle SAP Google E&Y Volvo Bosch Merck Fedex Shell Amgen Eli Lilly Roche AIG Abbott Amazon PwC T-Mobile Broadcom Bayer Pearson Titleist ConEd Pfizer NTT Data Schwab




Additional Marcus Insights